hmdb-database

原文涵盖的主题

• HMDB Database
• Overview
• When to Use This Skill
• Database Contents
• Core Capabilities
• 1. Web-Based Metabolite Searches
• 2. Accessing Metabolite Information
• 3. Downloadable Datasets

The Human Metabolome Database (HMDB) is a comprehensive, freely available resource containing detailed information about small molecule metabolites found in the human body. This skill should be used when performing metabolomics research, clinical chemistry, biomarker discovery, or metabolite identification tasks. HMDB version 5.0 (current as of 2025) contains: 220,945 metabolite entries covering both water-soluble and lipid-soluble compounds 8,610 protein sequences for enzymes and transporters involved in metabolism 130+ data fields per metabolite including: Chemical properties (structure, formula, molecular weight, InChI, SMILES) Clinical data (biomarker associations, diseases, normal/abnormal concentrations) Biological information (pathways, reactions, locations) Spectroscopic data (NMR, MS, MS-MS spectra) External database links (KEGG, PubChem, MetaCyc, ChEBI, PDB, UniProt, GenBank) Access HMDB through the web interface at https://www.hmdb.ca/ for: Text Searches: Search by metabolite name, synonym, or identifier (HMDB ID) Example HMDB IDs: HMDB0000001, HMDB0001234 Search by disease associations or pathway involvement Query by biological specimen type (urine, serum, CSF, saliva,

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